5 clinics ranked by DR ScoreUpdated 0 paid placements in this rankingHow we rank →
Top DR Score among weekend and evening dentists: Southern Colorado Dental Anesthesiology, DR Score 67, open 7 days until 8 PM.
Best for Saturdays: Comfort Dental, DR Score 53, open evenings until 7:30 PM and Saturdays until 1:30 PM.
Best for evenings: Comfort Dental Pueblo South, DR Score 53, open evenings until 7:30 PM and Saturdays until 1:30 PM.
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5 of Pueblo’s 73 clinics open Saturdays, Sundays or after 6pm, as of October 2026. 5 open on Saturdays, 1 on Sundays and 3 after 6pm. 1 are open 7 days a week.
| Rank | Clinic | DR Score | Rating (reviews) | Evenings / weekends | Best for |
|---|---|---|---|---|---|
| 1 | Southern Colorado Dental Anesthesiology | 67 | — | Evenings · Sat · Sun | Top DR Score among weekend and evening dentists |
| 2 | Comfort Dental | 53 | — | Evenings · Sat | Best for Saturdays |
| 3 | Comfort Dental Pueblo South | 53 | — | Evenings · Sat | Best for evenings |
| 4 | Dr.Dijana Elmejdoubi, Endodontist | 52 | 5.0★ (3) | Sat | — |
| 5 | Pueblo Modern Dentistry and Orthodontics | 47 | — | Sat | — |
Posted weekly hours for the highest-ranked clinics open on weekends or after 6pm.
Southern Colorado Dental Anesthesiology#1
Mon–Fri 6 AM–8 PM · Sat–Sun 6 AM–5 PM
Evenings · Saturday · Sunday
Mon–Fri 7:30 AM–7:30 PM · Sat 7:30 AM–1:30 PM · Sun closed
Evenings · Saturday
Pueblo Modern Dentistry and Orthodontics#5
Mon–Thu 7 AM–6 PM · Fri 7 AM–4 PM · Sat 7 AM–2 PM · Sun closed
Saturday
Ordered by DR Score, a 0–100 score from 6 published factors. Scores refresh weekly.
Ranked #1 in Pueblo
1225 N Main St Suite 206, Pueblo, CO 81003
Ranked #1 because of services and access: 17 of 17 services offered, open 7 days until 8 PM.
Based on access, services and profile completeness; Google ratings not yet collected.
General dentistryCleaningEmergency careRoot canalExtractionWisdom teethImplantsInvisalign+9 more
2025 US-50 #130, Pueblo, CO 81008
Ranked #2 because of services and access: 17 of 17 services offered, open evenings until 7:30 PM and Saturdays until 1:30 PM.
Based on access, services and profile completeness; Google ratings not yet collected.
General dentistryCleaningEmergency careRoot canalExtractionWisdom teethImplantsInvisalign+9 more
1221 S Pueblo Blvd, Pueblo, CO 81005
Ranked #3 because of services and access: 17 of 17 services offered, open evenings until 7:30 PM and Saturdays until 1:30 PM.
Based on access, services and profile completeness; Google ratings not yet collected.
General dentistryCleaningEmergency careRoot canalExtractionWisdom teethImplantsInvisalign+9 more
729 US-50, Pueblo, CO 81008
Ranked #4 because of its Google rating and review volume: 5.0★ from 3 Google reviews, the most Google reviews in Pueblo (3).
729 W US Hwy 50, Pueblo, CO 81008
Ranked #5 because of services and access: 17 of 17 services offered, open Saturdays until 2 PM.
Based on access, services and profile completeness; Google ratings not yet collected.
General dentistryCleaningEmergency careRoot canalExtractionWisdom teethImplantsInvisalign+9 more
As a Smile Generation Trusted office, we welcome you to Pueblo Modern Dentistry and Orthodontics! With state-of-the-art infection control procedures in place, our #1 goal is to keep you and your family safe. We provide comprehensive specialty services with advanced, proven technology and offer customized financial solutions for you. We are proud to be your complete Pueblo dental provider with services including Teledentistry, Same-Day Dental Crowns, Boost Whitening, Oral…
From Pueblo Modern Dentistry and Orthodontics's own description. Not part of the ranking.Answer 2 quick questions and we'll help you find a dentist that fits your needs, location and availability.
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This list covers the 5 Pueblo clinics that open Saturdays, Sundays or after 6pm. We scored 5 Pueblo clinics on 6 factors: reputation 45%, review volume 15%, recency 10%, access 15%, services 10%, profile completeness 5%. Data from Google listings and clinic websites, refreshed October 21, 2026.
Paid placement never changes a rank or score. Featured clinics are paid, labelled, limited to 3 and shown above the ranking, outside it.
| Factor | Weight | Computed from | In Pueblo data |
|---|---|---|---|
| Reputation | 45% | Bayesian-adjusted Google star rating | Measured |
| Review volume | 15% | log10(review count) against the city maximum | Measured |
| Recency | 10% | Share of reviews in the last 12 months | Measured |
| Access | 15% | Evenings, Saturday, Sunday, same-day/emergency, accepting new patients | Measured |
| Services | 10% | Services offered out of 17 | Measured |
| Profile completeness | 5% | Named dentists, years open, languages, insurance, photos | Measured |