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Dentists Open Saturday & Sunday in Greenville, SC (2026)

8 clinics ranked by DR ScoreUpdated 0 paid placements in this rankingHow we rank →

The short answer

  1. 1

    Top DR Score among weekend and evening dentists: AFC Urgent Care Bon Secours – Wade Hampton, 4.4★ from 1,011 Google reviews, open 7 days until 8 PM.

  2. 2

    Best for Saturdays: Greenville Dental Studio, 4.9★ from 188 Google reviews, open evenings until 8 PM and Saturdays until 12 PM.

  3. 5

    Best for Sundays: Piedmont Dental Center, 3.6★ from 7 Google reviews, open 7 days until 12 AM.

  4. 7

    Best for evenings: Denture Care of Greenville, DR Score 57, open 7 days until 12 AM.

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8 of Greenville’s 142 clinics open Saturdays, Sundays or after 6pm, as of October 2026. 8 open on Saturdays, 4 on Sundays and 5 after 6pm. 4 are open 7 days a week.

Top 8 weekend and evening dentists in Greenville at a glance

Top 8 weekend and evening dentists in Greenville at a glance
RankClinicDR ScoreRating (reviews)Evenings / weekendsBest for
1AFC Urgent Care Bon Secours – Wade Hampton804.4★ (1,011)Evenings · Sat · SunTop DR Score among weekend and evening dentists
2Greenville Dental Studio764.9★ (188)Evenings · SatBest for Saturdays
3Family Dental - Greenville674.2★ (662)Sat—
4Family Dental Care - Greenville635.0★ (10)Sat—
5Piedmont Dental Center603.6★ (7)Evenings · Sat · SunBest for Sundays
6HP Family Dentistry604.8★ (87)Sat—
7Denture Care of Greenville57—Evenings · Sat · SunBest for evenings
81800 Dentist Greenville47—Evenings · Sat · Sun—

Saturday, Sunday and evening hours in Greenville

Posted weekly hours for the highest-ranked clinics open on weekends or after 6pm.

The 8 weekend and evening dentists in Greenville, ranked

Ordered by DR Score, a 0–100 score from 6 published factors. Scores refresh weekly.

  1. Ranked #1 in Greenville

    #1 AFC Urgent Care Bon Secours – Wade Hampton

    2310 Wade Hampton Blvd, Greenville, SC 29615

    80/100

    Ranked #1 because of its Google rating and review volume: 4.4★ from 1,011 Google reviews, the most Google reviews in Greenville (1,011).

    • 4.4from 1,011 Google reviews
    Hours
    Mon–Fri 8 AM–8 PM · Sat–Sun 8 AM–5 PM

    General dentistryCleaningEmergency careRoot canalExtractionWisdom teethImplantsInvisalign+9 more

    Book appointment at AFC Urgent Care Bon Secours – Wade HamptonFull profile(864) 292-5915
    In their words

    When your family needs urgent medical care, our clinic is here to help. Our fully trained and highly experienced medical staff is ready to treat non-life-threatening, urgent medical issues. From wounds and broken bones to infections and family care needs, our walk-in clinic makes it convenient to get the quality medical care your family deserves. Our extended hours mean that we’ll be there for you, even after your doctor’s office is closed for the day. Open 7 days a week,…

    From AFC Urgent Care Bon Secours – Wade Hampton's own description. Not part of the ranking.

  2. #2 Greenville Dental Studio

    644 N Main St Suite 111, Greenville, SC 29601, United States

    76/100

    Ranked #2 because of its Google rating and review volume: 4.9★ from 188 Google reviews, 188 Google reviews.

    • 4.9from 188 Google reviews
    Hours
    Mon 7:30 AM–5 PM · Tue 8 AM–8 PM · Wed closed · Thu 10 AM–7 PM · Fri closed · Sat 9 AM–12 PM · Sun closed

    General dentistryCleaningEmergency careRoot canalExtractionWisdom teethImplantsInvisalign+9 more

    Book appointment at Greenville Dental StudioFull profile(864) 520-2942
    In their words

    We are a caring family and cosmetic dental practice. Our team, lead by Dr. Andy Bullard, takes the time to get to know each patient as an individual, so we know what matters to you. This helps us create a care plan that is unique to each of our patients, with a focus on quality and value. We are a family owned business, proudly serving Greenville, SC and the Upstate. New patients are always welcome.

    From Greenville Dental Studio's own description. Not part of the ranking.

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How we ranked Greenville dentists

This list covers the 8 Greenville clinics that open Saturdays, Sundays or after 6pm. We scored 8 Greenville clinics on 6 factors: reputation 45%, review volume 15%, recency 10%, access 15%, services 10%, profile completeness 5%. 32 were excluded (3 closed and 29 duplicate listings). Data from Google listings and clinic websites, refreshed October 21, 2026.

Paid placement never changes a rank or score. Featured clinics are paid, labelled, limited to 3 and shown above the ranking, outside it.

Read the full method: formula, sources and exclusions

DR Score factors and weights
FactorWeightComputed fromIn Greenville data
Reputation45%Bayesian-adjusted Google star ratingMeasured
Review volume15%log10(review count) against the city maximumMeasured
Recency10%Share of reviews in the last 12 monthsMeasured
Access15%Evenings, Saturday, Sunday, same-day/emergency, accepting new patientsMeasured
Services10%Services offered out of 17Measured
Profile completeness5%Named dentists, years open, languages, insurance, photosMeasured

Dentists Open Saturday & Sunday in Greenville, SC: frequently asked questions

Which dentists in Greenville are open on Saturday?

8 of the 8 clinics on this page open on Saturdays. The highest-ranked are AFC Urgent Care Bon Secours – Wade Hampton, Greenville Dental Studio and Family Dental - Greenville, and AFC Urgent Care Bon Secours – Wade Hampton opens 8 AM–5 PM.

Which dentists in Greenville are open on Sunday?

4 of the 8 clinics on this page open on Sundays. The highest-ranked are AFC Urgent Care Bon Secours – Wade Hampton, Piedmont Dental Center and Denture Care of Greenville, and AFC Urgent Care Bon Secours – Wade Hampton opens 8 AM–5 PM.

Which Greenville dentists are open late?

5 of the 8 clinics on this page stay open after 6pm on at least one weekday. Piedmont Dental Center has the latest weekday hours, until 12 AM on Mondays.

How are weekend and evening dentists in Greenville ranked?

Each clinic has one DR Score from 0 to 100, built from 6 published factors: reputation, review volume, recency, access, services and profile completeness. This page lists the 8 Greenville clinics that open Saturdays, Sundays or after 6pm, in DR Score order. No clinic pays for its position.

Update log for Greenville

  1. : DR Scores recalculated for 142 clinics.
  2. : 29 duplicate listings merged.
  3. : 3 closed clinics removed.

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